Research Paper Volume 14, Issue 7 pp 3129—3142

miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway

class="figure-viewer-img"

Figure 5. Effects of miR-29 on angiogenesis and fibrosis in vivo. The vessel sections were stained by hematoxylin and eosin. The section magnification was 4× and 20×, respectively. (A) H&E staining showed a higher degree of neovascularization (arrows) in miR-29 inhibition group than that in model group at 7 d, when the section magnification was 4×. (B) H&E staining showed less fibrotic areas in miR-29 inhibition group than those in model group at 28 d, when the section magnification was 4×. Results showed that miR-29 OE promoted angiogenesis and reduced fibrosis. Data were presented as mean ± SE (**P<0.01).