Research Paper Volume 14, Issue 7 pp 3233—3258

Figure 4. A gene set analysis shows the relationship between various molecules and ALDOA and FBP1 regulation. (A) Venn diagrams gather molecules related to ALDOA and FBP1 in LIHC. (B) Venn diagrams gather molecules related to ALDOA and FBP1 in LIAD. (C) The related Venn diagrams gather molecules related to ALDOA or FBP1 in LUAD or LIHC. (D) Gene ontology analysis predicts the biological functions of 30 genes. (E) An IPA linking molecules that interact between ALDOA and FBP1. (F) The heatmap shows the expression of downstream effectors related to ALDOA and FBP1 in TCGA LUAD/LIHC patients. (G) Spearman's correlation was used to rank the selected downstream effectors between ALDOA and FBP1 in LUAD/LIHC. The significance of the differences was analyzed using Xena Functional Genomics Explorer website. N or n is denoted as sample size.