Research Paper Volume 14, Issue 7 pp 3233—3258

Figure 5. Upstream regulators are involved in ALDOA and FBP1 regulation. (A) Venn diagrams showing the upstream regulators of ALDOA and FBP1 between LUAD and LIHC. (B) Venn diagrams gather upstream regulators with Spearman's correlation values over ±0.3 for ALDOA and FBP1. (C) The prognosis of upstream regulators in LUAD. (D) The prognosis of upstream regulators in LIHC. (E) The upstream regulators selected between ALDOA and FBP1 are increased in LUAD and LIHC. (F) The correlation between upstream regulators and downstream effectors of ALDOA and FBP1. The significance of the differences was analyzed using the GEPIA website. HA is denoted as the LIHC PanCancer Atlas dataset. HF is denoted as the LIHC Firehose Legacy dataset. LA is denoted as LUAD PanCancer Atlas dataset. LF is denoted as LUAD Firehose Legacy dataset. N is denoted the normal sample size. T is denoted as the tumor sample size. HR is denoted as hazard ratio.