Research Paper Volume 14, Issue 7 pp 3276—3292
An immune subtype-related prognostic signature of hepatocellular carcinoma based on single-cell sequencing analysis
Figure 9. The expression changes of modeling genes in immune cell differentiation. (A) The darker the blue, the earlier the differentiation, and the lighter the blue, the later the differentiation. (B) There are six different differentiation states, and differentiation state 1 is the earliest. (C) With the differentiation of immune cells, there was a trend that T cells first differentiated to B cells, and then to macrophages. (D) It was found that the expression of ANP32B and YBX1 genes was mainly increased, the expression of SPP1 was mainly decreased and then increased, and the expression of ADH4, PON1, FTCD, and SQSTM1 was mainly down-regulated.