Research Paper Volume 14, Issue 7 pp 3313—3324
SNP rs322931 (C>T) in miR-181b and rs7158663 (G>A) in MEG3 aggravate the inflammatory response of anal abscess in patients with Crohn’s disease
Figure 1. The expression of MEG3 (A) was progressively elevated while the expression of miR-181b was progressively suppressed (B) in the peripheral blood of Crohn’s disease patients carrying rs7158663 GG/rs322931 CC (N=76), rs7158663 AG+AA/rs322931 CC (N=62), rs7158663 GG/rs322931 CT+TT (N=36), and rs7158663 AG+AA/rs322931 CT+TT (N=32) genotypes (* P value < 0.05 vs. rs7158663 GG/rs322931 CC group; ** P value < 0.05 vs. rs7158663 AG+AA/rs322931 CC group; # P value < 0.05 vs. rs7158663 GG/rs322931 CT+TT group; 3 biological repeats).