Figure 1. Differential expression of circRNAs in normal and OA specimens. (A) Hierarchical clustering analysis of the differentially expressed circRNAs between 4 individuals normal and 4 individuals OA specimens; (B) Scatter plot of circRNAs expression between normal and OA specimens. The circRNAs below the bottom green line and above the top green line illustrate >2.0-fold changes between the normal and OA specimens. (C) Volcano plots of the differentially expressed circRNAs. The red point in the plot represents the differentially down or up-regulated circRNAs with statistical significance. (D–G) Expression of significant circRNAs in normal and OA specimens.