Figure 3. Circ_0000423 directly targeted by miRNA-27b-3p. (A) circRNAs-miRNA-mRNA network (B) Targeted miRNA-27b-3p relationship between Circ_0000423 and MMP-13; (C) Luciferase reporter gene assay confirmed the targeted relationship between Circ_00004234 and miRNA-27b-3p. Data are presented as mean ± SEM. *P < 0.05.