Research Paper Volume 14, Issue 8 pp 3617—3632

Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling

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Figure 1. Puerarin attenuates LPS-induced myocardial injuries in mice. (A) He staining sections were used to observe the pathological changes of heart tissues. The ratio of HW/BW (B) and HW/TL (B) is used to reflect the degree of cardiac edema. The concentrations of (C) CK-MB, (D) LDH and (E) cTnI in serum of mice were determined by ELISA. Data represent the mean ± SD. *P < 0.05 vs Control group; #P < 0.05 vs. LPS group; &P < 0.05 vs. LPS+Pue group.