Research Paper Volume 14, Issue 8 pp 3633—3651

Endothelin-1-mediated miR-let-7g-5p triggers interlukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients with diabetes mellitus

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Figure 1. Endothelin-1(ET-1)/creatinine expression is positively correlated with HbA1c expression in elderly patients with diabetes mellitus (DM). (AC) ELISA analysis indicates higher serum ET-1 and creatinine levels with higher HbA1c(R = 0.74). (D) Correlation between levels of HbA1c and diseases duration in elderly patients with DM (R = 0.58). (E) Serum ET-1 was higher with longer disease duration and lower bioelectrical impedance analysis values (R = 0.71). (F) Correlation between levels of serum creatinine and diseases duration with DM (R = 0.68).