Research Paper Volume 14, Issue 8 pp 3633—3651
Endothelin-1-mediated miR-let-7g-5p triggers interlukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients with diabetes mellitus
Figure 9. ET-1 played a critical bridging between sarcopenia and DM in elderly patients by triggering the myopathy through myocyte releases inflammation cytokines and affect the adipocyte metabolic meanwhile amplifying microenvironment injury.