Research Paper Volume 14, Issue 8 pp 3652—3665
microRNA-569 inhibits tumor metastasis in pancreatic cancer by directly targeting NUSAP1
Figure 3. miR-569 inhibited PC cell metastasis in vivo. (A) RT-qPCR showed miRNA agomir transfection efficiency. (B) In vivo bioluminescence imaging of representative animals from each treatment group 10 weeks after tumor cell inoculation. (C) Representative images of the liver of nude mice. Black arrows show metastatic tumor colonies in the liver. (D) HE staining of metastatic tumor colonies in the liver, magnification ×100. (* p < 0.05, ** p < 0.01, n = 5, Student’s t-test, means ± 95% CI).