Research Paper Volume 14, Issue 9 pp 3801—3812

In vitro and in vivo anti-lymphoma effects of Ophiorrhiza pumila extract


Figure 3. OPE suppresses A20 cell growth in vivo. (A) The effect of OPE on the volume of tumor derived by A20 cells. A20 cells were subcutaneously injected into the right oxter of Balb/c mice followed by the treatment with DMSO (NC), 15 mg/kg, or 45 mg/kg OPE (n = 4). The tumor volume was measured every other day. (B) The body weight of Balb/c mice after tumor cell inoculation and treatment. (C) The representative images of isolated tumors from Balb/c mice. Data are presented as means ± SD. (*p < 0.05; ***p < 0.001, compared to the untreated control).