Research Paper Volume 14, Issue 9 pp 3887—3909
Ox-LDL-mediated ILF3 overexpression in gastric cancer progression by activating the PI3K/AKT/mTOR signaling pathway
Figure 9. ILF3 promoted tumor cell growth in vivo. (A) Images of nude mouse tumorigenesis test after four weeks of implantation. Comparison of tumor volume between normal diets, high-fat diets, high-fat diets+statin and high-fat diets + ILF3 inhibitor-YM155. Tumors in high-fat diet group were bigger than normal diet group. Tumors in statin and ILF3 inhibitor-YM-155 groups were smaller than high-fat diet group. (B) Immunohistochemistry showed that the expression of ILF3 in normal diets, high-fat diets, high-fat diets+statin and high-fat diets + ILF3 inhibitor-YM155 groups. **P < 0.01, ***P < 0.001, ****P < 0.0001.