Research Paper Volume 14, Issue 9 pp 3921—3940

Figure 1. SC improves severe asthma. (A) H&E staining of lung tissues in the SA mouse model treated with SC. Scale bars = 100 μm. (B) The expression level of TNF-α in lung tissues was detected by ELISA assay. (n = 5) (C) The expression level of IL-1β in lung tissues was detected by ELISA assay. (n = 5) (D) The shape and size of the particles were evaluated using transmission electron microscopy. Representative pictures were shown. Scale bars = 100 nm. (E) Diameter distribution and particle concentration of exosomes were observed by nanoanalysis. (F) The expression levels of exosome markers and macrophage markers were detected by Western blotting. (G) Flow cytometry analysis of CD163+/CD68+ ratio. ^*P < 0.05; ^**P < 0.01.