Research Paper Volume 14, Issue 9 pp 3921—3940

Scorpion and centipede alleviates severe asthma through M2 macrophage-derived exosomal miR-30b-5p


Figure 6. M2Φ-Exos induced by SC carry miR-30b-5p to treat severe asthma. (A) H&E staining of lung tissues in SA model treated with SC and Exos-miR-30b-5p. Scale bars = 100 μm. (B) The expression level of IL-1β in lung tissues was detected by ELISA assay. (n = 3) (C) The expression of NLRP3 and caspase-1 was detected by Western blotting. (D) and (E) The expression levels of caspase-1 and NLRP3 were measured by immunohistochemistry. Scale bars = 100 μm. *P < 0.05; **P < 0.01.