Research Paper Volume 14, Issue 9 pp 3973—3988

Comprehensive analysis to identify noncoding RNAs mediated upregulation of maternal embryonic leucine zipper kinase (MELK) correlated with poor prognosis in hepatocellular carcinoma


Figure 7. MELK methylation (A) Differential expression of three DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) in the MELK high- and low-expression groups. (B) Evaluation of methylation by UALCAN and (C) DiseaseMeth version 2.0. (D) Survival analysis of methylation sites (cg14339556) in the MELK DNA sequence. (E) Analysis of methylation sites visualized by MEXPRESS. The central blue line indicates MELK expression.