Research Paper Volume 14, Issue 9 pp 3973—3988

Comprehensive analysis to identify noncoding RNAs mediated upregulation of maternal embryonic leucine zipper kinase (MELK) correlated with poor prognosis in hepatocellular carcinoma


Figure 8. MELK levels and immune cell infiltration in HCC. (A) Immune cell infiltration in relation to MELK copy number variations. (B) Correlation of MELK levels with B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells. (C) Association between MELK levels (HR = 4.636, 95% CI 1.170, 18.369, p = 0.029) patient OS at 60 months with increased neutrophil. (D) Association between MELK levels and patient OS at 60 months (HR = 6.202, 95% CI 1.578, 24.378, p = 0.009) with increased macrophage.