Research Paper Volume 14, Issue 10 pp 4376—4389

Figure 5. has_circ_0069313 was detectable in exosome. (A) Different exosomes were derived from different OSCC, the exosomes were then subjected to qRT-PCR and the relative has_circ_0069313 was detected (Student’s two-tailed paired test, ^**p < 0.01, ^***p < 0.001). (B) Immunoblot of exosome markers was detected. (C) Cal-27 and UM-2 were treated with UM1 derived exosomes and has_circ_0069313 was detected and normalized (Student’s two-tailed paired test, ^***p < 0.001). (D) Cal-27 and UM-2 were transfected with shRNAs and then treated with UM1 derived exosomes. The relative has_circ_0069313 level was detected (Student’s two-tailed paired test, ^***p < 0.001).