Research Paper Volume 14, Issue 9 pp 4050—4068

Figure 2. Development and validation of prognostic model based on HDAC genes. (A) Forest plot of univariate cox regression for HDAC genes in glioma patients. (B) LASSO regression of the 11 OS-related HDAC genes. (C) Cross-validation for turning parameters selection in the LASSO regression. (D) Kaplan-Meier survival curve of high- and low-risk groups from developed prognostic model based on 6 HDAC genes in TCGA. (E) Distributions of risk scores and survival time of glioma patients in TCGA. (F) PCA plot for high- and low-risk group in TCGA. (G) Kaplan-Meier survival curve of high- and low-risk groups from validated prognostic model based on 6 HDAC genes in CGGA. (H) Distributions of risk scores and survival time of glioma patients in CGGA. (I) PCA plot for high- and low-risk group in CGGA. (J and K) The receiver operating characteristic curve for predicting 1-year, 2-year, and 3-year survival rate of glioma patients in TCGA and CGGA.