Research Paper Volume 14, Issue 16 pp 6427—6448

An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

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Figure 1. Application of Eisenia bicyclis extract (EBE) enhances lifespan in female Drosophila. Lifelong application of 0.05% EBE (red) to adult female Drosophila (w1118) was compared to control flies of the same genotype (blue). The proportion of surviving animals is displayed against time (A). In (B), 0.1 % EBE was used under otherwise identical conditions. A similar analysis was performed with w1118 males and 0.05% EBE was applied (red) and compared with controls (blue) (C). Female flies of the yw strain were confronted with 0.05 EBE (red and compared to matching controls (blue) (D). (n > 100 per condition). Statistical analyses were done using a log-rank test. Ns means not significant, *** means p< 0.005, **** means p<0.001.