Figure 1. Viral diversity in AF. Rarefaction curves depicting viral contigs (A) and virus (B) numbers in control and AF specimens. Beta diversity by nonmetric dimensional scaling (NMDS) at the species level (C). Alpha diversity indexes, including the number of viruses (D), the Simpson index (E), the Shannon index (F), the Pielou index (G), and the Chao 1 index (H) at the species level in controls and AF cases. + denotes p-value < 0.01, *p < 0.05, and NS indicates no significant difference based on Wilcoxon rank-sum test.