Research Paper Volume 14, Issue 16 pp 6554—6566
Distinct microglia alternative splicing in Alzheimer's disease
Figure 6. Analysis of upstream splicing factors. (A) volcano plot of dysregulated splicing factors. (B) PPI networks of these 37 dysregulated splicing factors. (C, D) The first and second cluster of these splicing factors selected using MCODE app in Cytoscape. (E) Correlation between the firster cluster splicing factors and dysregulated transcripts involved in significant AS events. (F) Correlation between the second cluster splicing factors and dysregulated transcripts involved in significant AS events.