Research Paper Volume 14, Issue 16 pp 6716—6726

Psoralen downregulates osteoarthritis chondrocyte inflammation via an estrogen-like effect and attenuates osteoarthritis

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Figure 2. Expression of estrogen receptor target genes TFF1, CTSD, and PGR. E represents estrogen and I represents estrogen receptor antagonist. (A) Expression of TFF1 gene, (B) Expression of CTSD gene, (C) Expression of PGR gene. ** represents P < 0.01, *** represents P < 0.001 compared to control group.