Research Paper Volume 14, Issue 16 pp 6740—6755
Sulforaphane inhibits angiotensin II-induced cardiomyocyte apoptosis by acetylation modification of Nrf2
Figure 2. SFN inhibits Ang II-induced inflammation and oxidative stress. Western blot was used to detect the expression of inflammatory factors NF-κB (A), IKβ (B), TNF-α (C), oxidative stress indicators 3-NT (D), 4-HNE (E). Data were presented as the mean SD (n = 3). SFN has no effect on the activation of AT1 and NOX. Western blot and qPCR were used to detect the AT1 expression (F). Western blot was used to detect the expression of mp47phox and cp47phox (G). Data were presented as the mean SD (n = 3). *P < 0.05 vs control; # P < 0.05 vs Ang II.