Research Paper Volume 14, Issue 18 pp 7455—7469
Low-intensity focused ultrasound attenuates early traumatic brain injury by OX-A/NF-κB/NLRP3 signaling pathway
Figure 4. Low-intensity focused ultrasound (LIFUS) inhibited the levels of pro-inflammatory factors in traumatic brain injury (TBI) rat models by orexin-A (OX-A). (A) tumor necrosis factor-a (TNF-a), interleukin-1β (IL-1β), and interleukin-18 (IL-18) represent western blot protein bands, (B–D) are the gray values of TNF-a, IL-1β, and IL-18 bands, respectively, Results are expressed as mean±standard deviation (n=6, SD, *P<0.05, **P<0.01, ***P<0.001).