Research Paper Volume 14, Issue 22 pp 9020—9036
Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer
Figure 6. Role of PyroSig in predicting efficacy of immunotherapy. (A) Kaplan-Meier curves showing the survival analyses of high and low PyroSig groups in GSE17536 cohort. (B) Kaplan-Meier curves showing the survival analyses of high and low PyroSig groups in GSE37892 cohort. (C) Kaplan-Meier curves showing the survival analyses of high and low PyroSig groups in GSE38832 cohort. (D) Kaplan-Meier curves displaying the survival difference of high and low PyroSig groups in IMvigor210 cohort. (E) The ratio of clinical response types in high PyroSig and low PyroSig groups in the IMvigor210 cohort when treated with anti-PD-1 immunotherapy. (F) Differences in PyroSig between different clinical response types in the IMvigor210 cohort. (G) Survival analyses for PyroSig in GSE78220 anti-PD-1 immunotherapy cohort. (H) The ratio of clinical response types in high PyroSig and low PyroSig groups in the GSE78220 cohort when treated with anti-PD-1 immunotherapy. (I) Differences in PyroSig between different clinical response types in the GSE78220 cohort.