Research Paper Volume 14, Issue 22 pp 9056—9089

Circadian rhythm-related factors of PER and CRY family genes function as novel therapeutic targets and prognostic biomarkers in lung adenocarcinoma

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Figure 14. Correlations of PER and CRY family members expressions with different cytokine and immune checkpoint blockade treatments. (A) PER and CRY family member expressions in the LLC lung cancer model stimulated by different cytokines. (B) PER and CRY family member expressions in the LLC lung cancer model were not significantly related to immune checkpoint blockade treatment. * p<0.05, ** p<0.01, *** p<0.001; comparison results are summarized in boxplots.