Research Paper Volume 14, Issue 22 pp 9200—9209
Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans
Figure 1. Development of PA embryos from control and rapamycin groups. (A) The status of PA embryos in both groups at 0 h, 24 h, 48 h, and 108 h of culture. Scale bar, 75 μm. The comparison of (B) activation rates and (C) cleavage rates (D) blastocyst formation rates of PA embryos from both groups (n = 59). All data were expressed as mean ± SEM from three independent experiments. Abbreviations: Con: control; Rapa: rapamycin. *P < 0.05, **P < 0.01.