Research Paper Volume 14, Issue 22 pp 9200—9209
Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans
Figure 3. Effects of rapamycin on the levels of ROS and γ-H2AX of IVM oocytes. (A) The fluorescence images of ROS. Scale bar, 75 μm. (B) The levels of ROS in oocytes from both groups (fluorescence intensity value) (n = 43). (C) The fluorescence images of DNA and γ-H2AX in oocytes. Scale bar, 25 μm. (D) The intensity of γ-H2AX normalized to the mean DNA intensity in both groups (n = 29). **P < 0.01; ***P < 0.001.