Research Paper Volume 14, Issue 22 pp 9280—9299
The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers
Figure 5. Candidate circRNAs in human. (A) Homology analysis schematic of human and mouse circRNAs; (B) six circRNAs corresponding to mmu_circ_0000420 and four circRNAs corresponding to mmu_circ_0008035 in human; (C) qRT-PCR of circRNAs in human; (D) ROC of hsa_circ0101338 and hsa_circ0022426; Blue dotted lines represent diagnostic values for discriminating CRA from normal colon tissue; Red dotted lines represent diagnostic values for discriminating CRC from CRA; (E) circRNA-miRNA-mRNA network analysis of hsa_circ0101338 and hsa_circ0022426; (F) hsa_circ0101338 and hsa_circ0022426 can be early predictive biomarker of CRC. *p < 0.05; **p < 0.01; ***p < 0.001.