Research Paper Volume 15, Issue 8 pp 2891—2905
Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer
Figure 1. Identification of the candidate senescence-related DEGs in the TCGA-STAD. (A) Differentially expressed genes depicted by the volcano plot (red, up-regulated; blue, down-regulated in GC). (B) Heatmap depicting the mRNA levels of the 36 senescence-related DEGs between GC tissues and adjacent normal tissues. (C) Locations of the 36 senescence-related DEGs in chromosomes (red, up-regulated; blue, down-regulated in GC). (D) The mutation frequency of top 20 DEGs. (E) Bubble diagram demonstrated the top 6 enriched KEGG pathways of the 36 senescence-related DEGs. (F) GO enrichment analysis of the 36 senescence-related DEGs via biological process (BP), cellular component (CC) and molecular function (MF).