Figure 2. Scatterplots of DNAmFitAge versus age separated by sex. Pink indicates females, and blue indicates males. (A–F) Each panel corresponds to the performance of DNAmFitAge in one validation dataset displayed with Pearson correlation to chronological age and corresponding p-values. DNAmFitAge models applied to the same sex it was built in (i.e., DNAmFitAge built for females tested in females and DNAmFitAge built for males tested in males). DNAmFitAge is centered on chronological age with high correlation across all test sets.