Research Paper Volume 15, Issue 10 pp 4071—4083

Figure 4. PDGFD is a downstream target of miR-363-3p. (A) A binding motif of PDGFD within miR-363-3p predicted byStarBase3.0 (http://starbase.sysu.edu.cn/). (B) Luciferase activity in Huh7 and Hep3B cells transfected with miR-NC or miR-363-5p mimic. (C) PDGFD levels in Huh7 and Hep3B cells treated with NC-inhibitor or miR-363-5p inhibitor. (D) Relative expression of miR-363-5p in Huh7 and Hep3B cells treated with NC-inhibitor or miR-363-5p inhibitor. (E) PDGFD expression levels in Huh7 and Hep3B cells transfected with sh-NC, sh-PITPNA-AS1#1, or sh-PITPNA-AS1#1+miR-363-5p inhibitor were quantified by qRT-PCR and western blot. ^**P < 0.01, compared to the sh-NC group; ^{^^}P < 0.01, compared to the sh-PITPNA-AS1#1 group.