Research Paper Advance Articles

Figure 1. Palmitic acid promoted human retinal pigment epithelial cell migration. (A) ARPE-19 cell viability when treated with palmitic acid (PA) at the indicated concentrations for 48 h. (B) ARPE-19 cell wound healing ability when treated with palmitic acid at the indicated concentrations. Representative images of cells before (0 h) and after (48 h) the scratch are shown, and the relative wound closure was summarized. Scale bar, 200 μm. (C) ARPE-19 cell migration measured by transwell migration assays. Representative images are shown, and the invaded cell numbers per view field were summarized. Scale bar, 200 μm. (D) EMT-associated protein levels in the indicated ARPE-19 cells. Representative bands images are shown, and the relative protein levels were quantitated. n = 3 for each group; ^*P < 0.05, ^**P < 0.01, between the indicated groups.