Figure 2. Genetic and transcriptional alterations of FARGs in TCGA-LUAD patients. (A) Mutation frequencies of 38 FARGs. (B) CNV alteration frequency of 38 FARGs. (C) Location of the CNV alteration of 38 FARGs on chromosomes. (D) Expression of 38 FARGs between normal and tumor tissues. (E) The interactions among FARGs in LUAD are visually represented in the diagram. The interconnecting lines between FARGs signify their interdependence, with the line width representing the strength of the correlation between FARGs. Negative correlations are illustrated in green, while positive correlations are denoted in pink. ns, not significant, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.