Research Paper Volume 15, Issue 10 pp 4334—4362

Plasma exosome proteomics reveals the pathogenesis mechanism of post-stroke cognitive impairment

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Figure 1. Various characterizations of plasma exosomes. (A) The content of plasma proteins in 0.5 mL fraction sample. (B) Western blot analysis of the typical exosomal proteins, TSG 101, CD9, CD63 and CD81. (C) Transmission electron microscopy (TEM) image indicating exosome morphology. (D) A representative laser scattering microscopy image of isolated exosomes. (E) The Nanoparticle tracking analysis (NTA) result of the particle size distribution for isolated exosomes. (F) The size distribution of volume consistent with the size range of exosomes.