Figure 2. Genetic and transcriptional analysis of TRGs in SKCM. (A) The incidence of somatic mutations among the 33 TRGs in SKCM patients. (B) Frequencies of CNV gain and loss among TRGs. (C) Locations of CNV in TRGs on 23 chromosomes. (D) Expression levels of differentially expressed TRGs between normal and tumor samples. (E) Network of the comprehensive landscape of TRGs interactions in melanoma. The lines connecting the genes represent their interactions. Blue and red represent positive and negative correlations. *p < 0.05; **p < 0.01; ***p < 0.001.