Figure 4. Identification of gene clusters based on DEGs. (A) Heatmap demonstrated the relation between the two gene clusters and clinical conditions. (B) Expression levels of DEGs in the two gene clusters. (C) GO and KEGG analysis of DEGs. (D) The K-M curve showed higher survival in patients in cluster B. (p < 0.001). (E–G) Expression levels of PD-1, PD-L1, and CTLA-4 in the two gene clusters. *p < 0.05; **p < 0.01; ***p < 0.001.