Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer

Ranran Zhou; Jiawei Zhou; Bahaerguli Muhuitijiang; Xiangbo Zeng; Wanlong Tan

doi:doi:10.18632/aging.204753

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Research Paper

Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer

Figure 3. Identification of B cell-related genes. (A) 2075 cells from the primary BLCA were divided into 9 different cell types. (B) 13012 genes showing transcriptome expression difference between paracarinoma and BLCA samples were identified in the TCGA-BLCA cohort. (C) 163 genes were con-determined by the B cell marker genes’ analyses and genomic difference analyses. (D) The functional annotation of the 163 genes. (E) The protein-protein interaction network of the 163 genes.