Research Paper
Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer
Figure 6. BCRS was a robust and reliable prognosis predictor in BLCA. (A) The transcriptome expression levels of the model’s genes in the local BLCA samples, which was detected by real-time quantitative PCR. (B) A 0-or-1 matrix was established according to the mRNA expression values of the patients. (C) The BCRSs of the BLCA samples collected from the local hospital. (D) The distribution of survival statuses, follow-up duration, and BCRSs in the NH cohort. According to the same cut-off value (2.75), 19 cases were divided into low- and high-BCRS subgroup. (E) The patients with high BCRS exhibited unfavorable OS rates. (F) The comparison of BCRS and routine clinicopathological features to 6-. 12-, and 18-months’ OS. (G, H) Meta-analyses indicated that BCRS was a significant prognosis predictor, both using the continuous variables (G) and binary variables (H) for analyses.