Figure 4. The correlation between PFKFB3 expression and immune infiltration or immune checkpoint in pan-cancer. (A) Correlation analysis between PFKFB3 expression and immunological infiltration in pan-cancer by CIBERSORT algorithm. (B) Correlation analysis between PFKFB3 expression and immune checkpoint in pan-cancer. (C) The association between PFKFB3 expression and CD274, PDCD1LG2, and PDCD1, HAVCR2, SIGLEC15, TIGIT, and CTLA4 in PRAD. All data *P < 0.05; **P < 0.01; ***P < 0.001.