Figure 1. Screening of differentially expressed circRNAs (DECs) associated with malignant metastasis of ccRCC. (A) The normalization of samples in GSE100186 analyzed by GEO2R online tool. (B) The significant DECs between ccRCC cancer tissues and normal tissues. (C) The volcano plot of the DECs between ccRCC cancer tissues and normal tissues in GSE100186. (D) The normalization of samples in GSE137836 analyzed by GEO2R online tool. (E) The significant DECs between ccRCC cancer tissues and metastatic cancer tissues. (F) The volcano plot of the DECs between ccRCC cancer tissues and metastatic cancer tissues in GSE137836.