Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Longhui Fu; Beibei Yu; Yongfeng Zhang; Shuai Cao; Boqiang Lv; Yunze Tian; Huangtao Chen; Shijie Yang; Yutian Hu; Jinghua Hua; Pengyu Ren; Jianzhong Li; Shouping Gong

doi:doi:10.18632/aging.

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Research Paper

Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Figure 4. Validation of HSRGs by rat MCAO model and construction of prediction model. (A) TTC staining verification of rat MCAO model. (B) Validation of quantitative real-time PCR analysis. (C) Nomogram of HSRGs for predicting IS. A calibration curve (D), Clinical decision analysis (E, F), and ROC curve (G) of the nomogram.