Research Paper
Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke
Figure 6. The scRNA-seq reveals the expression of HSRGs in mouse brains. (A) Cluster analysis of scRNA-seq in GSE174574 dataset. Red represents the cells in the MCAO group and blue represents the cells in the Sham group. (B) Cell cluster identification was obtained in (A). Different colors represent different cell clusters, with a total of 9 identified. (C) Distribution of HSRGs expression in different cell clusters. Compared with the Sham group, red represents the high expression of genes in the IS group. (D) Quantified expression of HSRGs in different cell clusters. (E) The distribution of cell AUC value, an AUC value greater than 0.078 were adopted. (F) Distribution of HSRGs expression in different cell clusters based on AUC value. (G) Quantified AUC value of HSRGs in different cell clusters.