Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Longhui Fu; Beibei Yu; Yongfeng Zhang; Shuai Cao; Boqiang Lv; Yunze Tian; Huangtao Chen; Shijie Yang; Yutian Hu; Jinghua Hua; Pengyu Ren; Jianzhong Li; Shouping Gong

doi:doi:10.18632/aging.

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Research Paper

Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Figure 7. Intercellular communication analysis based on scRNA-seq. (A) The intercellular communication in the MCAO and sham groups. Microglia (B) and monocytes (C) as receivers assessed the cellular interactions with astrocytes and monocytes. (D) The TF enrichment plot in monocytes, microglia, and granulocytes.