Research Paper Volume 15, Issue 14 pp 7098—7123
Comparative analyses of the prognosis, tumor immune microenvironment, and drug treatment response between left-sided and right-sided colon cancer by integrating scRNA-seq and bulk RNA-seq data
Figure 6. Differences in mutation profiles and affected oncogenic pathways and their relationships with patient OS based on TCGA-COAD cohort. (A) Differences in the top mutated genes. (B) TP53 mutation status was significantly associated with OS in RCC patients. (C) TP53 mutation status was not significantly associated with OS in LCC patients. (D) The fraction of pathways and samples affected by the oncogenic pathways in RCC patients. (E) The fraction of pathways and samples affected by the oncogenic pathways in LCC patients. (F) TMB values were significantly higher in RCC than in LCC patients. (G) LCC patients with lower TMB values had better OS. (H) TMB values were not significantly associated with OS in RCC patients.