Research Paper
Causal pathway from telomere length to occurrence and 28-day mortality of sepsis: an observational and mendelian randomization study
Figure 2. Analysis of MR. There are scatter plots of the association between exposure SNP effect and outcome one. Analysis is conducted using the conventional inverse-variance-weighted MR method and complementary methods, including MR-Egger, weighted median, weighted mode approaches. Causal judgment depends on slope after each linear fitting. (A) Used to determine the causal effect of sepsis on LTL. (B) Utilized to determine the causal effect of LTL on sepsis. (C) Designed to judge the causal effect of LTL on 28-day mortality. Abbreviations: LTL: Leukocyte Telomere Length; MR: Mendelian randomization; SNP: single-nucleotide polymorphism.