Research Paper Volume 2, Issue 11 pp 791—803

Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma

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Figure 4. Intracranial regression of tumor growth by hUCBSC. (A) Nude mice with pre-established intracranial human glioma tumors (U251 or 5310) were treated with hUCBSC by intracranial injection (2x105). Fourteen days after hUCBSC administration, the brains were harvested, sectioned, and stained with Hematoxylin and Eosin. Bar = 2000μm (B) Characterization of hUCBSC in nude mice brain sections: Fourteen days after hUCBSC administration, the brains were harvested, sectioned and immunoprobed with mesenchymal stem cell markers CD29 using Alexa fluor-594 secondary antibody. (n = 3). Scale bar = 100μm.