Research Paper Volume 2, Issue 12 pp 969—980

Figure 3. Survival curves of transgenic glyoxalase strains on PASM 2% glucose. AMeiotic offspring of the three PaGlo1_OEx transformants T6, T8 and T12 is significantly short-lived compared to the WT (median lifespan: 16.2 d vs. 18.8 d). BPaGlo1/PaGlo2_OEx double mutant shows a moderate but significant increase of the median lifespan (15.8 d vs. 15.1 d). CPaGlo1 deletion strains are negatively affected which is demonstrated by their shortened lifespan compared to the WT (14 d vs. 18 d). Individual differences of WT growth rates observed in experiments conducted at different times are due to slight environmental variations.