Research Paper Volume 4, Issue 7 pp 509—520

Space/Population and Time/Age in DNA methylation variability in humans: a study on IGF2/H19 locus in different Italian populations and in mono- and di-zygotic twins of different age

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Figure 1. CpGs spatial localization and their methylation patterns.

(A) Spatial disposition of the amplicon analyzed in relation to functional elements. (B) Mean methylation level with the corresponding standard deviation for each CpGs considering the whole dataset. (C) Correlation matrix of CpG sites of IGF2_shore, IGF2AS, H19 and IGF2_island amplicons.